InteroPorc: Supplementary informations

Associated publication

If you publish work in which you have used InteroPorc, please cite the following publication:

Magali Michaut, Samuel Kerrien, Luisa Montecchi-Palazzi, Franck Chauvat, Corinne Cassier-Chauvat, Jean-Christophe Aude, Pierre Legrain and Henning Hermjakob,
InteroPORC: Automated Inference of Highly Conserved Protein Interaction Networks
Bioinformatics, 24(14): 1625-1631 pubmed


Motivation: Protein-protein interaction networks provide insights into the relationships between the proteins of an organism thereby contributing to a better understanding of cellular processes. Nevertheless, large-scale interaction networks are available for only a few model organisms. Thus, interologs are useful for a systematic transfer of protein interaction networks between organisms. However, no standard tool is available so far for that purpose.
Results: In this study, we present an automated prediction tool developed for all sequenced genomes available in Integr8. We also have developed a second method to predict protein-protein interactions in the widely used cyanobacterium Synechocystis. Using these methods, we have constructed a new network of 8,783 inferred interactions for Synechocystis.

Databases used in this study

Database Type Last update
IntAct Molecular interactions 2007-04-13
MINT Molecular interactions 2007-04-05
DIP Molecular interactions 2007-02-19
Integr8 Orthologous clusters 2007-12-04

Results generated in this study with the previous databases


IntAct (EBI)
Integrative Biology Laboratory (CEA)

Version history