Predict molecular interactions for your species
InteroPorc: Supplementary informations
If you publish work in which you have used InteroPorc, please cite the following publication:
Magali Michaut, Samuel Kerrien, Luisa Montecchi-Palazzi, Franck
Chauvat, Corinne Cassier-Chauvat, Jean-Christophe Aude, Pierre
Legrain and Henning Hermjakob,
InteroPORC: Automated Inference of Highly Conserved Protein Interaction Networks
Bioinformatics, 24(14): 1625-1631 pubmed
Motivation: Protein-protein interaction networks provide insights into the relationships between the proteins
of an organism thereby contributing to a better understanding of cellular processes. Nevertheless,
large-scale interaction networks are available for only a few model organisms. Thus, interologs are useful for a systematic
transfer of protein interaction networks between organisms. However, no standard tool is available so far for that purpose.
Results: In this study, we present an automated prediction tool developed for all sequenced genomes available in Integr8. We also have developed a second method to predict protein-protein interactions in the widely used cyanobacterium Synechocystis. Using these methods, we have constructed a new network of 8,783 inferred interactions for Synechocystis.
Databases used in this study
Results generated in this study with the previous databases
|Synechocystis||1148||1463||MITAB file [Details]|
|E. coli||562||58141||MITAB file [Details]|
|H. pylori||210||5562||MITAB file [Details]|
|S. cerevisiae||4932||1459||MITAB file [Details]|
|C. elegans||6239||10939||MITAB file [Details]|
|D. melanogaster||7227||13447||MITAB file [Details]|
|A. thaliana||3702||13743||MITAB file [Details]|
|M. musculus||10090||29678||MITAB file [Details]|
|R. norvegicus||10116||13469||MITAB file [Details]|
|H. sapiens||9606||17273||MITAB file [Details]|
- Jan 30, 2008 : InteroPorc is publicly available.
- Apr 14, 2008 : PSI25-XML file is also generated for predicted interactions .