Proline is a suite of software and components dedicated to mass spectrometry proteomics. Proline lets you extract data from raw files or identification engines, organize and store your data in a relational database, process and analyse this data to finally visualize and extract knowledge from MS based proteomics results.

Proline suite main features

The current version support the following features :

• Import identification results (OMSSA and Mascot files are currently supported). Once imported, search results can then be browsed and visualized through a graphical user interface.
• Validate search results using customizable filters and infer proteins identification based on validated PSM. Identification results issued from the validation can obviously be browsed and visualized.
• Combine individual search results or identification results to build a comprehensive proteome.
• Export identification results in different formats including standard exchange formats.

The software suite is based on three main components:

• A relational database management system storing the data used by the software in four different databases
• A web server handling processing tasks and web data access
• Two different graphical user interfaces, both allowing users to launch tasks and visualize their data: Proline Studio which is a rich client interface and Proline Web the web client interface

An additional component is used by administrators to setup and manage Proline (called ProlineAdmin).

Read the Installation & Setup documentation to install or start the different modules used by Proline.

Learn how to work with Proline with this typical use case example tutorial.

• Proline Studio
• Proline Web

Find quick answer to your questions in this how_to section.

Read the Concepts & Principles documentation to understand main concepts and algorithms used in Proline.

Both interfaces, Studio and Web, are based on a set of databases.

This procedure is detailed in the mzDB Documentation section.