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Proline Suite

Proline is a suite of software and components dedicated to mass spectrometry proteomics. Proline lets you organize your data, process and analyse them to finally visualize and extract knowledge from MS based proteomics results.

The current version support the following features :

  • Import identification results (OMSSA and Mascot files are currently supported). Once imported, search results can then be browsed and visualized through a graphical user interface.
  • Validate search results using customizable filters and infer proteins identification based on validated PSM. Identification results issued from the validation can obviously be browsed and visualized.
  • Merge individual search results or identification results to build a comprehensive proteome.
  • Export identification results in different formats including standard exchange formats.

The software suite is based on three main components:

  • A relational database management system storing the data used by the software in four different databases
  • A web server handling processing tasks and web data access
  • Two different graphical user interfaces, both allowing users to launch tasks and visualize their data:
  • ProlineStudio which is a rich client interface
  • ProlineWeb the web client interface

An additional component is used by administrators to setup and manage Proline (called ProlineAdmin).

Use Cases

usage scenarios including a Getting started example.

How-to

Find quick answer to your questions in this how_to section.

Concepts

Read the Concepts & Principles documentation to understand main concepts and algorithms used in Proline.

Setup and Install

Read the Installation & Setup documentation to install or start the different modules used by Proline.

Releases

Both interfaces, Studio and Web, are based on a set of databases.

Database Models

  • MSIdb contains data for a set of identification results. One MSIdb may contains all idenfication results for a given project. See MSIdb Documentation
  • LCMSdb. Contains LCMS maps for a given project. See LCMSdb Documentation
  • UDSdb contains information on projects, user and identification and/or quantitation experimental plans. See UDSdb Documentation
  • PSdb contains information on peptides and ptms seen over all projects (and MSIdb). See PSdb Documentation
  • PDIdb contains information on proteins (Accession history, fasta/dat representation, … ). See PDIdb Documentation

Raw file conversion to mzDB

This procedure is detailed in the mzDB Documentation section.

start.1376993768.txt.gz · Last modified: 2013/08/20 12:16 by 132.168.72.53