prolineconcepts:fdrestimator
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Table of Contents
FDR Estimation
There are many ways to calculate FDR. Proline implements few of them :
Peptide Spectrum Matches FDR estimation
- Default Estimator. The FDR is calculated using following rule
- if Search have been done on a concatenated Target/Decoy bank, FDR = 2 * nbr DecoyPSM / (nbr TargetPSM + bnr DecoyPSM ). PeptideMatches that matches a Target Protein and a Decoy Protein will be count in both case.
- if Search have been done on a separated Target/Decoy bank, FDR = nbr DecoyPSM / nbr TargetPSM.
- Competition Based FDR Estimator : Uses FDR described in Navarro et al. (JPR, 2009)
- TO BE DESCRIBED
Protein FDR estimation
prolineconcepts/fdrestimator.1380620786.txt.gz · Last modified: 2013/10/01 11:46 by 132.168.72.53
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