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prolineconcepts:proteininferer [2013/11/21 14:59]
132.168.72.225
prolineconcepts:proteininferer [2015/07/10 15:21] (current)
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 ====== Protein Inference ====== ====== Protein Inference ======
  
-All peptides identifying a protein are grouped in a ''​Peptides Set''​. A same Peptides Set can identify many proteins, represented by one ''​Proteins Set''​. In this case, one protein of this Protein Set is chose to represent the set, it is the ''​Typical Protein''​. ​+All peptides identifying a protein are grouped in a ''​Peptides Set''​. A same Peptides Set can identify many proteins, represented by one ''​Proteins Set''​. In this case, one protein of this Protein Set is chosen ​to represent the set, it is the ''​Typical Protein''​. ​
 If only a sub set of peptides identify a (or some) protein(s), a new Peptide Set is created. This PeptideSet is a subset of the first one, and identified Proteins are ''​Subset Proteins''​. If only a sub set of peptides identify a (or some) protein(s), a new Peptide Set is created. This PeptideSet is a subset of the first one, and identified Proteins are ''​Subset Proteins''​.
  
 {{:​prolineconcepts:​pepprotset1.png?​direct&​500|}} {{:​prolineconcepts:​pepprotset1.png?​direct&​500|}}
-  * In first example, P2 and P5 are identified by the same peptide set {pe1, pe4, pe5, pe8}. P2 was choosen ​as typical protein. One SubSet composed of {pe4, pe5, pe8} identify subset protein P4. +  * In first example, P2 and P5 are identified by the same peptide set {pe1, pe4, pe5, pe8}. P2 was chosen ​as typical protein. One SubSet composed of {pe4, pe5, pe8} identify subset protein P4. 
-  * In second example, ​An other Protein Set represented by P3, shares some peptides with ProteinSet represented by P2. Both ProteinSets have specific peptides.+  * In second example, ​Another ​Protein Set represented by P3, shares some peptides with ProteinSet represented by P2. Both ProteinSets have specific peptides.
   * Sharing could involve many ProteinSet as shown in example 3.   * Sharing could involve many ProteinSet as shown in example 3.
  
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 All Peptides Sets and associated ProteinSets are represented,​ even if there are no specific peptides. In both cases of above example, no choice is done on which ProteinSet / PeptideSet to keep.  All Peptides Sets and associated ProteinSets are represented,​ even if there are no specific peptides. In both cases of above example, no choice is done on which ProteinSet / PeptideSet to keep. 
-These ProteinSets could be filtered after inference (see [[.:rsvalidation#​Protein Sets Filtering|Protein sets filtering]]). ​+These ProteinSets could be filtered after inference (see [[.:protsetfiltering|Protein sets filtering]]). ​
  
  
prolineconcepts/proteininferer.1385042357.txt.gz · Last modified: 2013/11/21 14:59 by 132.168.72.225