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userguide:proteinfiltering [2010/04/14 11:23]
132.168.73.247
userguide:proteinfiltering [2010/11/05 11:08] (current)
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-====== ​Filter ​proteins or protein groups ======+====== ​How-to filter ​proteins or protein groups ======
  
-On a [[userguide:​contextdefinition| User Context]] it is possible to apply filters. Filter will mark as //hidden// (or //masked//) protein groups or proteins inside protein groups (depending on user choice) ​which respect ​user defined criteria. ​+On a [[userguide:​contextdefinition| User Context]] it is possible to apply filters. Filter will mark as //hidden// (or //masked//) protein groups or proteins inside protein groups (depending on user choice) ​according ​user defined criteria. ​
  
-  * If protein groups are filtered, the typical protein is considered but the whole group is (eventually) marked as //hidden//.  +  * If protein groups are filtered ​(i.e. "Apply to proteins"​ is NOT checked), the typical protein is considered but the whole group is (eventually) marked as //hidden//.  
-  * If proteins are filtered, each proteins of each protein groups are considered and (eventually) marked as //hidden//. If typical protein is set //hidden//, then another sameset protein ​is set as typical. If there is no more none //hidden// sameset then the whole protein group is set as //hidden//.+  * If proteins are filtered ​(i.e. "Apply to proteins"​ is checked), each protein from every protein groups are considered and (eventually) marked as //hidden//. If typical protein is //hidden//, then another sameset protein ​become the typical ​protein. If there is no more //visible// sameset ​protein ​then the whole protein group is set as //hidden//
 + 
 +The available filters are described in the how-to [[how_to:​proteinfiltering|filter proteins [groups] ]].  
 + 
 +If several filters are applied successively,​ the previous filter(s) is(are) not reset ("​cumulative"​ effect).
  
-The available filters are described in the how to [[how_to:​proteinfiltering|filter proteins [groups] ]].  
 ===== Impact of masking proteins [groups] in algorithms ​ ===== ===== Impact of masking proteins [groups] in algorithms ​ =====
  
-Once protein or proteins ​groups ​are marked as masked, ​they will be taken into account is some operations.+Once protein or a protein ​groups ​is masked, ​it will be taken into account is some operations. 
 ==== Masked protein groups ==== ==== Masked protein groups ====
  
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 The export operations (for AMT or reports) will only export valid (none masked) protein groups. This is also the case for ''​Contexts comparison''​ algorithm. ​ The export operations (for AMT or reports) will only export valid (none masked) protein groups. This is also the case for ''​Contexts comparison''​ algorithm. ​
-The other algorithms (change master / spectral count / protein grouping (peptide to consider) are not be impacted and (even if not necessary), they could be applied to all protein groups. 
- 
  
 +__**The other algorithms (change master / spectral count / protein grouping (peptide to consider) are not impacted and (even if not necessary), they could be applied to all protein groups.**__
 +==== Masked proteins====
  
-==== Hidden ​protein ​====+If user choose to apply filter on individual proteins, valid protein ​groups may contains valid and masked proteins. ​
  
-Hidden individual ​protein ​have more impact as in a //valid// protein group, only some of the proteins ​may be //valid//.+In visualization,​ the [[userguide:​proteingroups|protein ​group view]] identify ​//masked// proteins ​in sameset and/or subset lists
  
-In visualization, ​the protein group view //hidden// proteins are identified. ​ +For the export : 
-The export also have to considerate ​only none hidden proteins ​when exporting ​protein groups details or AMT db. +  ​* ​only  valid (none masked) protein are considered ​when exporting ​to AMT db. 
-The contexts comparison algorithm ​is impacted ​in the same way as when protein ​groups are masked : only valid protein ​should be considered. In the same way, change typical protein does not select //hidden// protein as typical ! +  * for reports, only one report ​is impacted ​(same subset detail report) and for each protein ​in valid protein ​groups, ​the masked property is indicated.
-The other algorothms (spectral count / grouping (peptide to consider) should not be impacted).+
  
-===== Hidden proteins group in browser =====+  * The ''​Contexts comparison''​ algorithm is impacted ​in the same way as when protein groups are masked : only valid proteins should be considered.  
 +  * ''​Change typical protein''​ operation does not select //masked// protein as typical !
  
-===== Hidden proteins in protein groups =====+__**The other algorithms (spectral count / grouping (peptide to consider) are not impacted.**__
userguide/proteinfiltering.1271236984.txt.gz · Last modified: 2010/04/14 11:23 by 132.168.73.247