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- | ====== Protein Groups ====== | ||
- | ===== Definition ===== | ||
- | A Protein Group is a collection of proteins identified by a set of peptides. In details, a Protein Group: | ||
- | * is represented by a master (or typical) protein | ||
- | * contains a collection of peptides identifying this master protein | ||
- | * contains a collection of proteins having the sameset of peptides | ||
- | * contains a collection of proteins having a subset of peptides | ||
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- | A Protein Group is quite similar to a Mascot protein hit, but operates at the [[contextdefinition#Context]] level. | ||
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- | Protein groups are obtained when running the [[peptidesandproteingrouping#Protein Grouping algorithm]] on a given context. | ||
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- | ===== GUI: Browsing protein groups ===== | ||
- | - Right-click on the User context of your choice (for which protein grouping has been executed) in the MSIExplorer window and select "Browse->Protein groups" in the context sensitive menu | ||
- | - Browse Protein Groups in the ContextExplorer window | ||
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- | {{:proteingrouping:contextexplorerwindow.png |Protein groups for a given Context}} Master protein is represented by {{proteingrouping:putative.png|Putative protein}}\\ | ||
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- | ===== GUI: Access protein group details ===== | ||
- | - Right-click on the protein group (master) of your choice in the ContextExplorer window and select "View Protein" in the context sensitive menu | ||
- | - The Protein Group window then show details about the master protein | ||
- | - If you select another protein from the sameset/subset tabs, the outline view showing peptides will update accordingly. | ||
- | {{:proteingrouping:proteingroupwindow.png|Protein Group window}} | ||
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- | {{proteingrouping:proteinGroupItem.png|Protein group item}} |